Abstract
This article relates contributions from the field of neuroscience to the basic functional model of ego states from transactional analysis. Among the diverse neuroanatomical and neurochemical operating systems that have been investigated and described, the author considers four to be the primary subcortical substrata of the three basic cerebral networks that neurologically sustain the manifestation of the three basic functional ego states. Previously, he also described the three main groups of neurological structures in the brain and their structural interplay in the ego states, considering them the cerebral substrata of the psychic organs.